Is it possible?
Gather unknown signals from deep, silent space · By
The only way to do this is with the reset slot button in the load menu. You can choose what to reset, but you'll need to reset events and objects for the most new content.
I advise you use the mailbox to send your precious plushies, engraved golden rings and warehouse full of shrimp to a temporary save, along with anything else you might want. Just remember that containers you put in there will be emptied!
Then you can safely reset events and objects, load it up, and keep your loot. BUT if you're far along the story, this might not be the best experience for you. Your Mileage May Vary!
To follow up on what the others have already said here, the game version doesn't really matter unless the update is a MAJOR one. You can still load very old saves (like back before the map changed to what we know today) and it'll load fine, but static objects like transformers and such will still be in places where the old map placed them to begin with, essentially barring you from interacting with them. Of course resetting would fix your issue in this case, but resetting the map or the base removes EVERYTHING inside of it, making it how it would look if you had just started the save. Usually I just start a whole new save from scratch per update since I'm gonna have to reset and use the mailbox anyways.