Top featured Downloadableon sale with Mouse support (40 results)
Explore Downloadable games with Mouse support on itch.io · Sell your Downloadable games with Mouse support on itch.io to have them show up here.
New itch.io is now on YouTube!
Subscribe for game recommendations, clips, and more
A romantic-comedy visual novel/dating simulator with a nostalgic touch of old-school RPG combat.
Simulation
A food-themed puzzle game where you have to arrange lunches in bento boxes!
Puzzle
SpaceChem is an obscenely addictive, design-based puzzle game about fake science!
Puzzle
The year is 1997. You used to be a hacker, but now you have the phage.
Puzzle
Master the intricate, physical machinery of the transmutation engine— the alchemical engineer’s most advanced tool!
Puzzle
Add up, multiply, clone, and divide your party members to beat the monsters on your path!
Puzzle
Boot up your Z5 Powerlance and dial into Last Call BBS, the last game from Zachtronics!
Puzzle
Psychedelic Roguelite Pong'em up where you rescue the Moon
Action
Last night I had a dream. I floated in darkness, immense, squamous. Then I fell in love with the majesty of colors.
Adventure
Build factories that assemble products for your alien overlords, and try not to die in the process.
Puzzle
Use the MOLEK-SYNTEZ to create small molecules with various pharmacological effects.
Puzzle
Join with the terminal and deactivate defective synthetics.
Interactive Fiction
Loading more games...