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Top Puzzlewith Mouse support Page 6 (14,047 results)

Explore Puzzle games with Mouse support on itch.io. Games that challenge the player with critical thinking to solve levels. · Upload your games with Mouse support to itch.io to have them show up here.

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I'm not going to ask what you would wish for. You already made your choice.
Adventure
You don't want to mess with Grek... but he does!
Survival
you ARE the Mini Map
Puzzle
Play in browser
Spacebar restaurant management simulation
Simulation
Play in browser
A puzzle horror game about repairing a facility
Puzzle
Play in browser
Navigation puzzle game at sea
Puzzle
A puzzle game starring Love & Hate
Puzzle
A short atmospheric 6DOF horror experiment
Adventure
Explore the indie gamedev makerspace MakeGame!
Simulation
Play in browser
3D Puzzle Platformer Game About a Cute Bird Finding His Brother But Finds out That ...
Puzzle
Survival horror game
Survival
A lonely puzzle game in space
Puzzle
Play in browser
Ruya
$3.99
A game about dreams and motherhood
Puzzle
Play in browser
SHENZHEN I/O: BUILD CIRCUITS. WRITE CODE. RTFM.
ZachtronicsVerified Account
Puzzle
Submachine is a hand-drawn point and click puzzle adventure game.
Adventure
SpaceChem is an obscenely addictive, design-based puzzle game about fake science!
ZachtronicsVerified Account
Puzzle
First person puzzle solving using the power of elemental weaponry!
Action
A Two Player Adventure
Rusty LakeVerified Account
Adventure
a puzzle game set in liminal locations, with procedurally generated rooms.
Adventure
Use the MOLEK-SYNTEZ to create small molecules with various pharmacological effects.
ZachtronicsVerified Account
Puzzle
A game about transforming!
Puzzle
Minimalistic Tower Defense
Play in browser
Retro 1st-person point & click inside a dream-like train station.
Adventure
This is an unusual escape game. 2nd work in the series.
Puzzle
Play in browser
Take to the skies in your balloon ship and explore a world of floating islands.
Adventure
Defuse bombs under a time constraint.
Puzzle
Frostfire is an abstract match-3 puzzle game combining both new and familiar mechanics to create deeper gameplay.
Puzzle
A warmly wistful adventure about reconnecting nature, friendship and hidden pasts
Tiny Red CamelVerified Account
Adventure
Visit a spaceship, The Ark, and discover the truth behind the Black Cubes.
The IcehouseVerified Account
Adventure
Minesweeper but with infinite recursion.
Puzzle
You're a retired paleontologist. Collect fossils & solve puzzles in your old garage!
Puzzle
​The year is 1997. You used to be a hacker, but now you have the phage.
ZachtronicsVerified Account
Puzzle
Brew gender potions & graduate together(?) with your bestie(?)
Visual Novel
Play in browser
A secret agent escape room. Stop enemy spy Ruby La Rouge before she escapes.
Adventure
A social networks simulator where you have to investigate and manipulate to get your ultimate goal: PIZZA
Simulation
Your friend invites you to his house for a sleepover with a certain set of rules
Interactive Fiction
Play in browser
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