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Card Game

Featuring gameplay centered around the strategic use of cards, these games often involve building decks, managing resources, and executing tactical decisions. Players might encounter various mechanics such as turn-based combat, deckbuilding, and card collection.

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Top Card Gamewith Mouse support (1,857 results)

Explore Card Game games with Mouse support on itch.io. Featuring gameplay centered around the strategic use of cards, these games often involve building decks, managing resour · Upload your games with Mouse support to itch.io to have them show up here.

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A turn-based, deck-building roguelite focused on dice combinations!
Card Game
Play in browser
Stack monsters into delightful combos.
Strategy
Play in browser
You've never played blackjack with cards like these!
Card Game
Play in browser
A tower defense focused on card combos, mechanical synergies, and a limited tower count
Strategy
You are the Social Democratic Party of Germany in 1928. Can you stop the Nazis from taking power?
Interactive Fiction
Play in browser
Turn your humble farm into a majestic kingdom in this tranquil, enchanting card-based city-building adventure
Strategy
Play in browser
A turn-based roguelike (alpha version)
Card Game
Play in browser
A roguelike "deck crawler"
Card Game
Play in browser
deckbuilding survivors
Shooter
Play in browser
As a missionary, you go to spread your message to a wicked man. He, however, wants to play a card game with you.
Card Game
The inventory management roguelike! Collect rare items, organize your backpack, and vanquish your foes!
Role Playing
Play in browser
Card Game
Play in browser
Rogue-like card game
Card Game
Play in browser
Can you help provide the medieval town of Grudziądz with water?
Card Game
Play in browser
Destroy the invading titans from within. Roguelike deckbuilder.
Card Game
Play in browser
Roguelike auto-battler
Card Game
Play in browser
An autobattling solitaire Balatro-like!
Card Game
Defeat the HOST in a death game to claim your freedom.
Card Game
Play in browser
Marvel Champions LCG
Card Game
All seven Zachtronics solitaire games, updated with new 4K graphics, plus one brand new Tarot-themed solitaire variant.
ZachtronicsVerified Account
Card Game
A Half-Life card game heavily inspired by Inscryption
Card Game
An introspective deck-builder about friendship, travel, and collecting snacks.
Echodog GamesVerified Account
Card Game
A standalone 1-4 player remake of the Picture Poker minigame from the Nintendo DS game "New Super Mario Bros"
Card Game
​An homage to Art Fight, draw your cards, summon characters from various artists and duel for your favourite team!​
Card Game
Play in browser
A survival horror/roguelite/dark decision-making card game hybrid where morality conflicts with survival.
Card Game
Play in browser
Dice, cute animals, scary forest
Card Game
Play in browser
Roguelike Deck-Building On The Go! Can you reach the top of the tower?
Card Game
Play in browser
Build a thriving island colony one building at a time.
Strategy
Play in browser
A Deck-Building RPG Card Game!
Card Game
P.T. recreated with HyperCard
Card Game
Card-based debating RPG and occult mystery thriller.
Card Game
Collect forbidden trading cards. Summon a demon. End the world.
Adventure
Roguelike dungeon crawler card game.
Card Game
Play in browser
RPG + Card Game
Role Playing
Play in browser
Simple 40-card solitaire with multiple game modes
Card Game
Play in browser
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