New & popular freetagged 2D and Mouse only (3,352 results)
3,352 results
Explore games tagged 2D and Mouse only on itch.io · Upload your games to itch.io to have them show up here.
New itch.io is now on YouTube!
Subscribe for game recommendations, clips, and more
View Channel
An idle clicker about a spinning chip
Strategy
Play in browser
Moderate a stream chat in this hectic game!
Simulation
Play in browser
Come get the highest score taking orders and making sushi!
Simulation
Play in browser
Build your own hero company, maybe even save the world along the way?
Simulation
Play in browser
Shoot bubbles on the platform and keep the tree in balance
Simulation
Play in browser
A Tower Defense game where the player only has control over a single tower at any point in time.
Strategy
Play in browser
Pirate Software Game Jam 16 2025 Submission
Platformer
Play in browser
Take control of of the weather to help people thrive!
Simulation
Play in browser
Guide a nuclear missile through an asteroid belt to destroy an invading alien ship.
Play in browser
Dive into the witch's cauldron and pop the malicious spirits possessing the bubbles! Good luck to you rat
Loading more games...