New & popular paidwith Mouse support from 2021 (726 results)
Explore games with Mouse support from 2021 on itch.io · Sell your games with Mouse support from 2021 on itch.io to have them show up here.
New itch.io is now on YouTube!
Subscribe for game recommendations, clips, and more
View Channel
Death and Taxes
$12.99
You are the Grim Reaper on an office job. Save the world.. or condemn it to damnation?
Simulation
Placebo Love
$8.99
A lonely young man is guided by a silent Muse to solve the mystery behind his two Doppelganger Soulmates.
Visual Novel
Gritty tooth-punk rogue-lite funs, with a few pretty good puns.
Action
Lush and vibrant visuals, the game features original hand-drawn artwork.
Visual Novel
Glass Hearts
$19.99
Gripping psychological thriller Yaoi game full of difficult choices. Can you trust your own mind?
Visual Novel
Acolyte
$10.99
A narrative ARG/Detective game that gives you your own digital assistant.
Interactive Fiction
say goodbye to whatever you want to leave behind this year.
Interactive Fiction
A relentless choose & click fast strategy game with over 700k generated levels!
Action
30 minutes of plot-driven "space-invaders" entertainment
Action
In Tower Defense: Monster, you'll have to defeat the army of invading monsters.
Strategy
A Visual Novel about a guy who gains the ability to travel back in time
Visual Novel
A skiing experience like no other with a unique control system and purely physics driven gameplay!
Sports
Loading more games...