Skip to main content

Indie game storeFree gamesFun gamesHorror games
Game developmentAssetsComics
SalesBundles
Jobs
TagsGame Engines

Filter Results

(Clear)
Tags

2D

Uses two-dimensional "sprites", 2D images created and used on a flat plane, as opposed to the three-dimensional models or environments found in 3D games.

Suggest updated description

Latest freetagged 2D and plague (30 results)

Explore games tagged 2D and plague on itch.io. Uses two-dimensional "sprites", 2D images created and used on a flat plane, as opposed to the three-dimensional models o · Upload your games to itch.io to have them show up here.

New itch.io is now on YouTube!

Subscribe for game recommendations, clips, and more

Dance, Dance & Hyper Dance
Play in browser
Immune Defence: Can You Stop the Pandemic Inside Your Body?
Simulation
Poison the food and water supply to infect the colonists with plague, raid their pantries to stay alive.
Survival
Play in browser
Platformer
Play in browser
A small tale about a mouse plague at a cheese factory
Adventure
Play in browser
The Black Plague is upon us, or is it something else entirely? Can you find THE CURE?
Simulation
Play in browser
(DEMO) Travel the sewers of Old London and collect the skulls of Bubonic Plague Victims.
Play in browser
Discover the bleak truth of the floral mine shaft in this dark and atmoshperic action platformer.
Platformer
Blast your way through these putrid catacombs.
Action
Play in browser
A fun arcade pixel art game with puzzle elements about a plague doctor trying to bring hope in bad times
Puzzle
Play in browser
A 5-10 minute story based game on The Great Plague of London, 1665-5.
Role Playing
Play in browser
Short one room bitsy game about being socially distanced... and bored.
Simulation
Play in browser
A puzzle game, to raise awareness about risks of COVID-19, in a play&learn way.
Puzzle
Play in browser
Small strategy game about rebuilding castle and preparing for a plague.
Strategy
Play in browser
Little 2D game for the Ludum Dare 46
Action
Play in browser
Time is running, you have 40 days to keep the town alive. Can you do it?
Platformer
Play in browser
Save the town, keep the population content. How many can you keep alive?
Adventure
Play in browser
You are Ted, a plague doctor. Help your community!
Strategy
Action
Play in browser
Two player PVP neighbour battle: Who will win the Beauty-Garden-Award?
Fighting
Protect healthy eggs from the plague
Action
Play in browser
Mow down zombies, collect blood and upgrade your sweet carriage!
Adventure
Run away from rats!
Action
Destroy the virus.
itch.io now on YouTube!