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Sci-fi

Science-fiction. Commonly including things like aliens, advanced technology, and settings of outer space or distant planets. 

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sci-fi

Tower Defense

A type of game where the player builds defensive structures to stop waves of enemies from reaching and destroying their base. Towers can be equipped with many kinds of weapons, but generally are unable to move. Resources earned by defeating enemies allow for more towers to be built.

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Toptagged Sci-fi and Tower Defense Page 3 (276 results)

Explore games tagged Sci-fi and Tower Defense on itch.io · Upload your games to itch.io to have them show up here.

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Unique towers and enemies, in game shop system, global upgrades and specials!
Strategy
Strategy
Play in browser
Orbital Tower Defense Game. Save Mars from the Alien Invasion by constructing Orbital Array with units called Antons.
Strategy
Play in browser
Defend your mining outpost with the help of your mech!
Action
Deploy and equip your mechs with the guns needed to defend your chalupa from the alien bugs
Strategy
Play in browser
A tower defense game in a crater with nice explosions
Strategy
Inspired by the story of the same name by Bradbury
Strategy
Play in browser
Tower Defense 3D
Action
Play in browser
Defend humanity against the A.I. threat in this instant action real-time strategy, tower defense hybrid.
Strategy
Automate, strategise and thrive in extracting gold from an alien planet. An automation, tower defense roguelike.
Strategy
Sci-Fi 3D Tower Defense Game with an upgrade system and Elemental Reactions
Strategy
Deploy and configure your fleet and fight your way through the enemy lines.
Simulation
Project Astra Dominium is a Tower Defense game with Basebuilding and Automation elements.
Strategy
HTC Vive Tower Defense Game
Shooter
Fend off unrelenting hordes of robots!
Strategy
Strategy
Play in browser
Real-time sci-fi strategy game with unusual mechanics.
Strategy
Beat the toughest levels with the right combinations and bonus damage
Adventure
A defensive centered game, all random gear stats, explore the vast universe.
Strategy
Play in browser
Prepare to defend the solar system against invaders!
Strategy
FPS/Tower Defense Hybrid
Shooter
Tower defense focused on colony management and turret micro-management
Strategy
Tactical 3D game with dynamic gameplay.
Strategy
Protect the Voronium mining operation at all cost, build defense towers and operate them simultaneously. VR exclusive.
Shooter
Tower Defense + Resource Managment
Strategy
Play in browser
Game is inspired by astroneer and no man's sky. Sci fi top down shooter survival
Survival
A xenobotanist is tasked with restoring the natural ecosystem of a far-off wasteland planet and defending the base.
Survival
Play in browser
Defend your nation, answer the call for help and maintain order against the enemy alliance
Strategy
a special 3D tower defense game
Adventure
Fight to survive against the tide of robots bent on your destruction!
Strategy
Place towers to defend the space station against asteroids!
Play in browser
Direct your legions of sci-fi mice throughout the galaxy in conquest of cheese!
Strategy
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