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Sci-fi

Science-fiction. Commonly including things like aliens, advanced technology, and settings of outer space or distant planets. 

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sci-fi

Tower Defense

A type of game where the player builds defensive structures to stop waves of enemies from reaching and destroying their base. Towers can be equipped with many kinds of weapons, but generally are unable to move. Resources earned by defeating enemies allow for more towers to be built.

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Top rated
tagged Sci-fi and Tower Defense (91 results)

91 results

Explore games tagged Sci-fi and Tower Defense on itch.io · Upload your games to itch.io to have them show up here.

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GIF
Second Earth
A base building game focused on economy and defence.
Robbie Fraser
Rated 4.5 out of 5 stars
(134 total ratings)
Strategy
GIF
Scavenger of Dunomini 🤖
$6
In bundle
Match-3 Trash Pile Defender
PUNKCAKE Délicieux 🥞
Rated 4.8 out of 5 stars
(20 total ratings)
Puzzle
GIF
Reflector: Laser Defense
roguelike colony management in an hour
MichaelMakesGames
Rated 4.8 out of 5 stars
(12 total ratings)
Strategy
Play in browser
Orbital Defense Program
An orbital tower defense game with roguelite elements.
CyreneGames
Rated 4.6 out of 5 stars
(30 total ratings)
Strategy
Play in browser
GIF
TAG: Tower Attack Game
Tower Defense, but you're not defending!
Sugar Potato
Rated 4.7 out of 5 stars
(15 total ratings)
Strategy
Play in browser
satOlite (Playdate)
$5
An orbital Tower-Defense game exclusively for Playdate
LuBu
Rated 4.7 out of 5 stars
(9 total ratings)
Strategy
Deep in the Void
$4.99
2D Factory/Strategy Game
Whackland Studios
Rated 4.4 out of 5 stars
(13 total ratings)
Strategy
Planet Z33
First person tower defense
Lana Lux
Rated 4.6 out of 5 stars
(7 total ratings)
Survival
COSMODROME.v.03.14.22
jameschappfillmore@gmail.com
Rated 4.5 out of 5 stars
(6 total ratings)
Strategy
Play in browser
Surge Breaker
How quickly can you obliterate the crawler menace in this top-down action-strategy hybrid?
sbteam
Rated 4.3 out of 5 stars
(6 total ratings)
Action
Play in browser
Deep Sands Delivery
Ludum Dare 53 Game
Ryan
Rated 4.3 out of 5 stars
(6 total ratings)
Action
Play in browser
Last Star Playtest
Space roguelite with tower defense elements. Defend your solar core against hordes of alien invaders.
Nordm4n
Rated 5.0 out of 5 stars
(4 total ratings)
Action
Play in browser
Core Defense
$9.99
A roguelike tower defense game with a dash of deckbuilding.
ehmprah
Rated 5.0 out of 5 stars
(4 total ratings)
Strategy
Rogue Station Defense
Roguelike tower defense with deep customization
Cladcake
Rated 4.2 out of 5 stars
(6 total ratings)
Strategy
Play in browser
Super Space Siege
a 2D intense tower defence game made for GBJam 11 packed with action and levels to beat
BlueEagle421
Rated 4.2 out of 5 stars
(6 total ratings)
Strategy
Play in browser
Rust & Dust
Defend your base by hacking & transforming your enemies.
r00k
Rated 4.2 out of 5 stars
(5 total ratings)
Strategy
Starship Scale
Blast your way through space and scale up your ship!
Anahat
Rated 5.0 out of 5 stars
(3 total ratings)
Action
Play in browser
Regain Earth: First Strike Demo
Take the challenge of surviving waves of increasingly difficult evil mutants! Grab a friend to hunt and slay them.
TheFlow - Regain Earth
Rated 5.0 out of 5 stars
(3 total ratings)
Shooter
Orbit Overload
Defend your world from an expanding star, strategize, build, and survive the cosmic threat!
TheFreePlant
Rated 5.0 out of 5 stars
(3 total ratings)
Strategy
Play in browser
Space Defender
An action- packed, sci-fi tower defense game.
nikthegreat2020
Rated 5.0 out of 5 stars
(3 total ratings)
Strategy
Play in browser
UNDEFENDED!
A 3d-platforming tower defense action game.
euclidean-whale
Rated 4.3 out of 5 stars
(4 total ratings)
Platformer
Play in browser
Dinosaur Protection Program
Dinosaur Protection Program
horlof
Rated 4.7 out of 5 stars
(3 total ratings)
Action
Play in browser
Final Front Planetary Defence
Planet Tower Defence Game!
coomzy
Rated 5.0 out of 5 stars
(2 total ratings)
Strategy
Destroy The Monoliths [alpha v0.6]
Radiant Sloth
Rated 5.0 out of 5 stars
(2 total ratings)
Action
Def
Tower Defense Devolved
OMGWTFGAMES!1!!
Rated 5.0 out of 5 stars
(2 total ratings)
Strategy
Coupler
A Tower Defence game with an electrical twist!
DoubleTom
Rated 5.0 out of 5 stars
(2 total ratings)
Strategy
サイバーガード - Cyber Guard
Endless Rouge-like Tower Defense with cute Cyber Guards
Devsagi
Rated 5.0 out of 5 stars
(2 total ratings)
Strategy
Play in browser
COSMODROME.v.03.14.22DESKTOP
$10
jameschappfillmore@gmail.com
Rated 5.0 out of 5 stars
(2 total ratings)
Strategy
Play in browser
CityDefense
A mixture of a normal tower defense game and a city builder.
JOrbits
Rated 5.0 out of 5 stars
(2 total ratings)
Strategy
Chalupa Defense Force
Deploy and equip your mechs with the guns needed to defend your chalupa from the alien bugs
Kronikle
Rated 5.0 out of 5 stars
(2 total ratings)
Strategy
Play in browser
Junk Raider
When RTS meets Tower Defense in a cartoon style. Fight monstrous mutants to save the Humanity’s fate.
TealRocks
Rated 4.5 out of 5 stars
(2 total ratings)
Strategy
Power Defense (JAM EDITION)
Help defend the world in this cute Tower Defense RPG! Do you have the power to save the tower?
KP
Rated 4.5 out of 5 stars
(2 total ratings)
Role Playing
Play in browser
SSTR - All Experiences - Demo
Dabster Entertainment
Rated 3.7 out of 5 stars
(3 total ratings)
Puzzle
Smol Defense Alpha Demo
Fend off horders of enemies with turrets and stuff.
ｈｅｉｎｎ
Rated 4.0 out of 5 stars
(2 total ratings)
Strategy
Space Defender V0.5.9
Manolo Studios
Rated 4.0 out of 5 stars
(2 total ratings)
Shooter
Re-Refinery
A game revolving around refining trash for resources and protecting your base from enemies
Thor30056
Rated 5.0 out of 5 stars
(1 total ratings)
Strategy
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