Top rated games with Mouse support tagged 2D

Explore games with Mouse support tagged 2D on itch.io. Uses two-dimensional "sprites", 2D images created and used on a flat plane, as opposed to the three-dimensional models o · Upload your games with Mouse support to itch.io to have them show up here.

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Look through a stranger's computer. A horror puzzle game.

qwook

Rated 4.9 out of 5 stars

(2,437 total ratings)

Puzzle

Play in browser

Backpack Hero

$19.99

The inventory management roguelike! Collect rare items, organize your backpack, and vanquish your foes!

Thejaspel

Rated 4.8 out of 5 stars

(2,092 total ratings)

Role Playing

Play in browser

Therapy with Dr. Albert Krueger

dino999z

Rated 4.8 out of 5 stars

(2,414 total ratings)

Interactive Fiction

Vampire Survivors

Mow thousands of night creatures and survive until dawn!

poncle

Rated 4.8 out of 5 stars

(1,439 total ratings)

Action

Play in browser

GIF

Exhibit of Sorrows

Have fun with seemingly friendly dolls and a not so friendly clown.

adayofjoy

Rated 4.8 out of 5 stars

(1,716 total ratings)

Simulation

Play in browser

OneShot

$10

A surreal puzzle adventure game with unique mechanics / capabilities.

Future Cat Games

Rated 4.9 out of 5 stars

(1,114 total ratings)

Role Playing

GIF

her tears were my light

a love story between time and space

NomnomNami

Rated 4.8 out of 5 stars

(1,211 total ratings)

Visual Novel

Play in browser

one night, hot springs

a young transgender woman goes to the hot springs.

npckc

Rated 4.8 out of 5 stars

(1,292 total ratings)

Visual Novel

Cryptid Coffeehouse

the (moth)man, the myth, the legend: now in sexy dateable human form

nukes

Rated 4.9 out of 5 stars

(601 total ratings)

Visual Novel

Syrup and the Ultimate Sweet

a candy alchemist finds a candy golem in her basement workshop

NomnomNami

Rated 4.8 out of 5 stars

(1,287 total ratings)

Visual Novel

Play in browser

Lo-Fi Room

Build lo-fi beats in this hidden object / rhythm game

Bearmask

Rated 4.7 out of 5 stars

(1,602 total ratings)

Rhythm

Play in browser

Contract Demon

an angel summons a demon. they fall in love.

NomnomNami

Rated 4.7 out of 5 stars

(1,458 total ratings)

Visual Novel

Play in browser

Blackout

Point & click adventure set in a spooky house!

FRESH

Rated 4.8 out of 5 stars

(1,073 total ratings)

Adventure

Play in browser

GIF

HOW WE KNOW WE'RE ALIVE

A point-and-click mystery set in the bible belt of Sweden

Motvind Studios

Rated 4.8 out of 5 stars

(935 total ratings)

Adventure

good morning!

a morning routine simulator ｡･:*:･ﾟ★,｡･

cnnmon

Rated 4.6 out of 5 stars

(2,450 total ratings)

Simulation

Play in browser

what body?

Clean your room!

bun_tired

Rated 4.7 out of 5 stars

(1,218 total ratings)

Play in browser

Time is Solid Here

A horror puzzle game about helping people move on.

AlgebraFalcon

Rated 4.8 out of 5 stars

(854 total ratings)

Puzzle

Play in browser

P.E. Noire

Point and Click Softboiled Detective Story

Picogram

Rated 4.7 out of 5 stars

(1,218 total ratings)

Puzzle

Play in browser

Cafe in the Clouds

Two cooks turn dream eaters when troubled, sleepless townsfolk seek their unusual services.

Cafe Nemo

Rated 4.8 out of 5 stars

(818 total ratings)

Visual Novel

That's not my Neighbor

$2.99

Work as a doorman in a building infested with doppelgangers.

Nacho Sama

Rated 4.7 out of 5 stars

(1,223 total ratings)

Simulation

Someone Stole MY LUNCH!

A short comedy visual novel about your lunch and a thief... both of which are hot.

Studio Clump

Rated 4.7 out of 5 stars

(930 total ratings)

Visual Novel

GIF

Red Handed

A stealth game where you have to get caught

Bad Piggy

Rated 4.6 out of 5 stars

(1,325 total ratings)

Action

Play in browser

GIF

Mr.TomatoS

In bundle

Welcome to my game, buddy!

OXTORD games

Rated 4.8 out of 5 stars

(675 total ratings)

Educational

Little Chef

A fun and cute 2D physics-based cooking game with a focus on experimentation and discovery.

Julien

Rated 4.7 out of 5 stars

(823 total ratings)

Simulation

Play in browser

(Don't) Open Your Eyes

A short, horror visual novel about a midnight visit from a strange being, who demands you open your eyes. Will you?

Via

Rated 4.6 out of 5 stars

(1,215 total ratings)

Visual Novel

GIF

hi no homo

realistic simulator of awkward people saying hi

angela he

Rated 4.6 out of 5 stars

(1,697 total ratings)

Simulation

Play in browser

GIF

Monster Girl Maker

Character creator themed around cute and creepy monster girls!

Emmy- GhoulKiss

Rated 4.6 out of 5 stars

(1,339 total ratings)

Role Playing

Play in browser

Arcade Spirits

$20

A Romantic Comedy Narrative Game

Fiction Factory Games

Rated 4.7 out of 5 stars

(968 total ratings)

Visual Novel

Tender Lovin' Cannibal [DEMO]

"Did you know... I love you?"

Rae1347

Rated 4.9 out of 5 stars

(232 total ratings)

Visual Novel

Return of the Tentacle

Sequel to the Point&Click-Adventure "Day of the Tentacle"

catmic

Rated 4.9 out of 5 stars

(237 total ratings)

Adventure

Dark Nights

Nothing is what it first appears.

pinlin

Rated 4.7 out of 5 stars

(576 total ratings)

Visual Novel

BASES LOADED

baseball survivors

kindanice

Rated 4.7 out of 5 stars

(587 total ratings)

Action

Play in browser

Signs of the Sojourner

$19.99

An introspective deck-builder about friendship, travel, and collecting snacks.

Echodog Games

Rated 4.7 out of 5 stars

(510 total ratings)

Card Game

Pyre

$19.99

Pyre is a party-based RPG from the creators of Bastion and Transistor.

Supergiant Games

Rated 4.8 out of 5 stars

(353 total ratings)

Role Playing

Among Us

An online and local party game of teamwork and betrayal for 4-15 players

Innersloth

Rated 4.5 out of 5 stars

(1,552 total ratings)

Dog Wash

Wash a Doggo!

Tony LindoRock

Rated 4.7 out of 5 stars

(574 total ratings)

Simulation

Play in browser

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Top ratedGamesGamesToolsGame assetsComicsBooksPhysical gamesAlbums & soundtracksGame modsEverything elsewith Mouse support tagged 2D (11,377 results)

New itch.io is now on YouTube!

Top rated
Games Tools Game assets Comics Books Physical games Albums & soundtracks Game mods Everything else
with Mouse support tagged 2D (11,377 results)