Top ratedwith Mouse support tagged Sci-fi (1,698 results)
1,698 results
Explore games with Mouse support tagged Sci-fi on itch.io. Science-fiction. Commonly including things like aliens, advanced technology, and settings of outer space or distant plan · Upload your games with Mouse support to itch.io to have them show up here.
New itch.io is now on YouTube!
Subscribe for game recommendations, clips, and more
View Channel
Gather unknown signals from deep, silent space
Rated 4.9 out of 5 stars
(2,977 total ratings)Simulation
CrossCode
$19.99
A retro-inspired 2D Action-RPG set in the distant future
Rated 4.8 out of 5 stars
(435 total ratings)Role Playing
A cyberpunk and solarpunk adventure-romance that explores a world where one side is forever day and the other, night.
Rated 4.9 out of 5 stars
(287 total ratings)Visual Novel
A lonely sea otter surviving in a world ravaged by the mysterious monsters known as the I.C.O.
Rated 4.8 out of 5 stars
(277 total ratings)Visual Novel
Chisel through a layer cake of thousand-year-old civilizations.
Rated 4.8 out of 5 stars
(243 total ratings)Role Playing
I dared PewDiePie to dare me to make him a game in 14 days. This is the result.
Rated 4.8 out of 5 stars
(250 total ratings)Adventure
Build a futuristic space colony!
Rated 4.7 out of 5 stars
(423 total ratings)Simulation
Play in browser
Cosmic Horror About Alien Abductions
Rated 4.8 out of 5 stars
(249 total ratings)Adventure
A cyberpunk and solarpunk adventure-romance that explores a world where one side is forever day and the other, night.
Rated 4.7 out of 5 stars
(288 total ratings)Visual Novel
hadopelagic false light
Rated 4.9 out of 5 stars
(99 total ratings)Interactive Fiction
Play in browser
The classic tale of cheese, goodwill and transdimensional fridge theft.
Rated 4.6 out of 5 stars
(401 total ratings)Adventure
An underwater Survival Horror Adventure - but what lies beyond the ocean's deepest depths?
Rated 4.7 out of 5 stars
(286 total ratings)Action
Build a vast interstellar empire in 30 minutes flat.
Rated 4.6 out of 5 stars
(394 total ratings)Strategy
Play in browser
Chronicles from 4.012 is a multi-choice otome game and visual novel, that takes place in a cyberpunk world.
Rated 4.8 out of 5 stars
(165 total ratings)Visual Novel
CAUTION: Escape from this supervillain at your own risk...
Rated 4.8 out of 5 stars
(117 total ratings)Visual Novel
Fran Bow
$14.99
A young girl struggles with mental disorder and an unfair destiny.
Rated 4.8 out of 5 stars
(142 total ratings)Adventure
Gaslight eldritch horrors or die trying
Rated 4.7 out of 5 stars
(165 total ratings)Visual Novel
Tsundere Amnesiac AI x Pathetic Space Pirate
Rated 4.7 out of 5 stars
(192 total ratings)Visual Novel
A LGBT-friendly cozy sci-fi cooking/dating sim about making friends, finding love, and running a diner in deep space
Rated 4.8 out of 5 stars
(105 total ratings)Visual Novel
A sci-fi horror adventure game.
Rated 4.7 out of 5 stars
(154 total ratings)Adventure
Play in browser
Award-winning, rhyming point'n'click adventure
Rated 4.5 out of 5 stars
(342 total ratings)Adventure
To get ahead in business, you need to Make Something of Yourself.
Rated 4.9 out of 5 stars
(45 total ratings)Visual Novel
The world is ending, and you are still paying rent. A future history.
Rated 4.9 out of 5 stars
(56 total ratings)Interactive Fiction
Play in browser
Tactical stealth meets top-down mecha combat and excessive destruction
Rated 4.9 out of 5 stars
(45 total ratings)Action
Transistor
$19.99
Discover the world of Transistor, a sci-fi-themed action RPG from the creators of Bastion.
Rated 4.8 out of 5 stars
(73 total ratings)Action
A small game about greeting cards and life choices.
Rated 4.6 out of 5 stars
(136 total ratings)Visual Novel
A twisted saturday morning cartoon adventure
Rated 4.7 out of 5 stars
(127 total ratings)Adventure
beautiful twine compilation
Rated 4.9 out of 5 stars
(50 total ratings)Adventure
Fight your way through the vampire castle hidden behind the moon!
Rated 4.7 out of 5 stars
(96 total ratings)Action
Play in browser
SEEK MEANING FROM MEMORY
Rated 4.9 out of 5 stars
(41 total ratings)Interactive Fiction
Play in browser
Gay disaster mech pilots killing fascists, Season 2
Rated 4.8 out of 5 stars
(63 total ratings)Visual Novel
NOT FOR INDIVIDUAL RESALE
Rated 5.0 out of 5 stars
(26 total ratings)Interactive Fiction
Play in browser
Use caution when opening attachments, clicking links, or responding.
Rated 5.0 out of 5 stars
(29 total ratings)Interactive Fiction
Play in browser
Loading more games...