I think with some adjustments, it probably could since there's no specific flavoring or hard mechanical changes to the roles!
As well, as a sort of follow-up; could the Dowager and the Tutor still work as characters in a game that uses these? Sort of as like a potential 'older figure' for a game that focuses on in-house structures and stuff?
Those roles very much have to be adults so if you're having adult MCs, sure.
