There are definitely Men and Women in the game. Most of them are just never interacted with.
Brothel Madame, Shopkeeper, Witch in the cottage, Elf by the lake, Toy merchant, Helena and Tentacle witch are women.
Normal innkeep, Drunkard, Gloryhole guys and several random one-off NPC's are manly men.
The game's inhabitants act like dickgirls are unusual, but they are the vast majority.