Like when you open the game file. You will usually have a "game name.exe " or something like that to open the game but mine is "game name-32.exe". I can't play any games with a file that has the 32.exe thing
It's rather easier to download games using the Itch.io launcher; I've been using it for the past two years almost and it's much more easier to download the games and their updates; You can choose if you want to update the said games or not.
