The first room of the mansion, right? I think I know what the problem is.
The game is made in Fusion 2.5, so I don't have any sort of error logs or anything, but since you mentioned it was the first room that crashes, I have a theory on what is going wrong. I have this gradient layering effect I'm using and the game runs in Direct 3D 9. Having the options to lower or turn off those settings might solve the issue, as you were able to play the opening bit in the woods just fine (which has no layered gradient effects). I will be sure to add these options to the Options box in my first patch run this weekend.