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It's the same you beat any other enemy. If the red orc is giving you trouble, try putting on different armor or weapons. Craft some strong health potions. Try some niche potions like the sleeping mist to get an edge. You got options.

Right. My still most powerful weapon is Razit's spear as it still does great damage to enemies and doesn't have any negative stats. As for the armor, I'm still wearing the lizard's chest plate, and the reason for that is the same as the Razit's spear. I also buy a headband for that extra 1 perception, and DON'T forget to wear the free collar from Hyao as it has all the stats. It's optional, and change or load your equipment to battle mode first before entering the fight. Changing while in a battle might give the enemy a chance to hit you, so it's recommended to do it

Now for the pants and boots. I suggest getting these items from Northcrest market. It'll lower your appearance stats and be a bit expensive, I know, but you don't need it that much since you can just spam lust potions (you can change if you want after the battle and buy the brief from Rose too).

For the crotch is the enchanted cock ring. You'll get it from the lizard tribe and enchant it with the healer at night

The last is for the ring. You can only get this if you haven't explored the cave of the second part of the junkyard or if you haven't flooded it. You need to place the air plate to be able to swim at the left side of the map and get this special ring. It has some defense and special stats (like fire resistance and more), but it also has negative stats for appearance. I suggest having a backup save in case you mess up because you'll not get it if you flood the part where you need to go first. If you already flooded it or got it, I suggest getting the leather bracelet instead from Bernard, 

This is what I wear when in battle, and it's okay if you don't want to copy it.

Make sure to always have sleeping mist, health potions, antitoxin, lust potions (optional), anti-bleeding ointment (optional), muscle ointment (optional), spectral sirup (for wrath fever), energy drink, energy drink (strong), and restraint potion. Another optional thing to do but highly recommended is brewing strength potion, agility potion, endurance potion, and focus tea (drink them before entering the fight).

Don't forget to grind exp by fighting, make love with the enemies, or do some quest for some juicy exp and coins.

That's all.