Enjoying the premise so far. Any criticisms I have are covered in other comments already so I won't bother with them here. Though I personally don't really mind the reactor minigame and find it requires just enough finesse to be quite fun actually. Beyond that, I absolutely would love to see perhaps fewer worms, but perhaps more expressive animations as they wriggle their way in and out, and each contributes more to belly/breast size. Also, love the all the way through option, by personal preference, but you may need to offer a way to plug one's mouth automatically, or make it harder for worms to force their way out of it to counteract the nature of it.
In short, you have the potential for a really hot game here, and I can't wait to see how it pans out. ^_^
The reactor game is currently patched to be easier than before- as long as you're not on the Surgery setting. Worm entry/exit animations are planned, but extra work- may take a bit for that to show up, but it's been requested.
Eventually, I'd like to add items & choices for actively keeping 'friends' in hands-free, like one-way/normal plugs- I have a plan for how to set that up, but it won't be until there's more 'friend' variety.