Yes this is safe.
Viewing post in Five Nights At Freddy's comments
Your computer probably says that it doesn't recognize the file and that you may be at risk but I have downloaded a LOT of itch.io games and I have never gotten hacked. It just means that your computer doesn't recognize that type of file. But if it ACTUALLY says in big, bold letters, "YOU'VE BEEN HACKED." Then yes I'd suggest deleting it. Overall, you could download the itch.io app to download it instead. the app doesn't make you extract any files or anything, you just click install and it does all the work for you! Trust me, if this game was a virus it would've been taken down a LONG TIME AGO! Hoped this helped! :)