If you haven't unlocked the Guildenstern is Dead mission, here are some notes that helped me: "Get on the boat, don't get distracted by the captain or you'll miss Guildenstern's event. You don't need to cooperate with the captain to survive: if Guildenstern has enough information, she can deal with the captain herself." Also something about doing "Irma's Ire" at the same time, but I can't swear that helped.