Will the decisions at the end of Chapter 1 open up different routes or interactions with each girl? It didn't seem so with what is in the 1.5B demo of Chapter 2 but I really hope that it will be a thing in the future.
The decisions you make will definitely affect the end result of the game. Not so much create different routes in chapters 2 and 3, but I am working on dialogue differences depending on what you've done. Its just not a priority right now.