I love the disease that turns skin in to bark, the bugbear squatters holding up a bridge construction, and the giant skeleton in Halfskull Bay. I did not expect the disease to be contracted by a miner having relations with a dragon. I enjoyed that there was a sense of humor throughout the booklet.
I like the colors you used for the hexcrawl map, but I think a different color for the forests/plains would help visually differentiate them, especially on the larger map on the 1st page.