At this point, it's best to complete all the main quests with them. But you can avoid paying them too much attention. That is, ask the fortune teller what needs to be done and do it. At the same time, don't invite this couple to have fun with monsters.
Considering that the game's plot is still, in general, quite linear... Such a choice can block progress in the game. Therefore, such things should be done carefully. Perhaps, closer to version 1.0, players will have the opportunity not to communicate with some of the characters. This is still a secret for everyone except the author of the game.