if you really can't and don't want to make a new game, you can edit your save to make anna seduce adrian. the rid of this event is 2265, you simply replace "false" by "true" at this line 
if you try this: you should have 2 line where rid 2265 appear unless you have more than one save (ctrl+f and write 2265) [you can open the save with notepad/i use VScode in screenshoot but they do the same thing] (all saves are stored in the same file in order, the first time one line appear it's save1 if the exact same line appear later it's save2)
