Unfortunately, I'm only about half sure, I generally run everything on firefox by default on my laptop (desktop has a heavily modified version of ff and is always goofy so I can't compare the results) and only switch off if I can't otherwise do something. Usually it's a Unity compatibility fault, so I can't remember anything that would have gone wrong here before. That being said, I don't know for a fact that I wouldn't have not thought twice and just switched off if something didn't work the first time around.