My first thoughts are that it should be slightly more clear where you're supposed to go at the beginning, like a button that makes the protagonist think about where to go. Or a quest log. Another is that the zombie sprites are tiny compared to the normal people. There seems to be an unlimited amount of energy drinks and medkits on day one but that's probably a good idea for a demo.
Maybe make it more clear if something's an item you can interact with, sign you can read, or other thing to examine. Also maybe use compass directions like west and north east instead of left and right side. I use mouse to move and this skips dialogue when it pops up, so maybe make it so you only advance dialogue while clicking a specific prompt.
Reading the journal after Reed wakes up in the room that begins "It's been days since They brought Reed in all bloody and bitten up" it then shows Reed using a different character sprite than his usual one. maybe it's old? also occurs when examining the old rope ladder outside that building