The gym curse is directly tied to orientation, so that one is unavoidable. The nature of Charlton is to push everyone into hetrosexual relationships (plus patriarchal and sexist mentality), but big part of the game is to offer options for players to push back, rebel and ultimately stop the people doing this, so there will be options to avoid / push back on this. I would say it's definitely not inevitable, but some curses / magical items will increase orientation.