Yes, but at least then you can get un-stuck with the help of tasks. It's also possible to not have enough Wood, Axes, or Hardwood for any of the 3 to produce anything, but that is when the task board comes back and future quests become quittable.
I guess that also means I don't need to lock Extra-normal upgrades, since if you buy an upgrade too early, you can do tasks to get what you lost
Once you have a good handful of Radiative upgrades, you will probably never get soft-locked or need to grind for resources to get un-stuck