Me and my wife enjoyed playing this, and it was so quick we played a second time right away!
Printing instructions were very useful, however it was hard to cut the cards with scissors because there were no trace lines between cards. Next time you make PnP files, it would be great to facilitate those without a paper cutter as well ;)
Your rules don't mention who starts first or what happens if a tile stack is empty, but other than that the rulebook was great and covered everything needed.
I don't enjoy memory elements in games, so that part of your game didn't work for me. The rest of the gameplay was optimizing mission points while avoiding elements you've already seen in Research cards, which felt a bit flat and repetitive, but the optimization part was engaging enough.
On a second play we felt that there weren't many options to differentiate strategy. My wife tried to play less for objectives and more for getting points at the end, while I was juggling both like the first time, and she lost by 2 points, making her feel that her strategy was suboptimal.
Overall, great production quality, great rulebook, good gameplay experience, maybe not a lot of replayability