Very neat game. Very fleshed out for an alpha. I personally haven't encountered any problems, except maybe needing a save for long missions. I was also a little confounded about how the fertilizer stuff actually synergizes with the other buildings, so I had to experiment with that before understanding how it works. Descriptions are often overlooked by devs, and, although it's no big issue here, it could be improved a little.
One more thing that confused me a little is the waste dumps. I didn't let my hospital and oxygen scrubber fill up, so I don't know if they can get clogged up. However, once you store waste in the dump, it's there to stay. So, once you start with fertilizer, you still rely on having active waste production from buildings; you can't take waste from the dump. This seems very counter-intuitive, although I suspect it has to do with how buildings work. Either way, it's not a big thing, but maybe something worth considering.
Another example of descriptions, now that I'm thinking about it, is the hospital and oxygen scrubbers. It isn't clear to me if it requires a community center to be in its radius, or simply the houses around it. My guess is it's the former, but I'm not sure.