It doesnt really have negitive effects on her physical state other than the weaknesses of the quirk she is using. take a quirk like vine hair for instance, one she got at the sports festival, its useful and great, but what if someone like Endevor shows up? then shed have to swirch quirks or get burnt. oh btw, she does go to UA, shes like a spy for Shigi (a name she gave him) and the rest of the Leauge