Hello Zanilo,
As a personal opinion, the games I develop should be played on the console for which it was created. Playing a 1MB game on systems that support games with a lot of GB, detracts from the gameplay and gaming experience.
Gameboy games has a lot of limitations, starting with the color palette, resolution, size, etc.
It's just a personal opinion. This is why I am in favor of maintaining the cartridge and play the games in the original console despite the fact that the users are very few.
Have a nice day!
DP