As of this comment, I'm on the latest version.
Whenever I change a keybinding, it doesn't stay for me. What I'm doing is changing the item wheel to another key since my Z key is broken, and whatever (working) key I choose doesn't bring up the little wheel. I have tried making it upper and lower case, neither works.
Another bug I've noticed is that I commonly drag my mouse out of the game screen, although the game is still in progress and not in the escape menu. I don't have mouse keys or anything enabled, so I don't know of a way to fix (except full, but I'm on a bad laptop so I'm trying to keep my frames as high as possible with a smaller windowed screen)