Just ran a "one-shot" (it's going to slip into a second session) and it went really well! Granted it's a group I've played with before and people who have very similar sensibilities as me so it was stacked in my favor, but it basically played out as a best case scenario of what I was expecting, so I'm really happy about it. For the most part the mechanics worked well; I'm sure they could be refined further but the core of it worked well. The players were able to understand the abilities and the karma system, and I really liked how an encounter could be framed either as a Save challenge or a "Combat" and how that affects how things play out, that was probably the stand-out part of it imo even if someone were not at all interested in the setting or the karma system.