I personally don't like the "manage shop" style of game and sorry but I didn't had patience trying to make new potions hahaha but overall is a really cool game, really nice art, and is really fun. I actually love games where you need to combine elements to create things(my favorite is doodle god)
I really think you could improv things like more guidance about where you can and should click( at the start I felt kinda lost) and some way to know what ingredients could be used to create something new( for example in doodle god you know that water and earth = mud), I believe that book was supposed to do this but I didn't understand.
Anyway, good job!