If you are getting the title screen then I guess stuff has been installed and it can run.
The game is set up for windows, but you can use it with other operative systems- if you have python and pygame installed (not necessary with windows).
Do you get music? If not that could indicate that something is broke.
This game only takes keyboard input. So you should not use the mouse at all. (it can still be used on the x-button to close the game)
So you should use the "n" key for a new game.
One thing I could think of is if the game has lost focus. Then the key input would not work. To get focus back you can mouse click anywhere on the title screen.
I hope any of that works for you.