Just got a bug that ruined my only good cave run :'( for whatever reason as I took morphine to get a buffer in case a musca tries to yeet me, the needle didnt vanish, got stuck in my PCs hand, and I was unable to drop it manually or switch weapons until she broke. Might have to do with taking drugs too quickly one after another (was trying to minimise the time needed to get my weapons re equipped before the next wave).
Not sure if it's already a known/reported bug but I hope I helped anyway :)