Glad you're enjoying it!
Kinda depends how far away from Denvorn you want to get, I guess. You can play with the core rules and just ignore the faction/setting-level stuff that starts at page 33 of the v1.0 doc, but the whole game is tied pretty closely to the setting. If you want a *completely* distant experience you should probably just use the core rules, create custom playbooks, and consider how the campaign-level mechanics might be changed to fit your setting.