They can lead us to madness and therefore to death:
- alpha wolves,
- alpha werewolves,
- the slime bosses,
- the queen mother of bees,
- Tank,
- the Tar creatures,
- the tree of perdition in the abyss (depending on our mental/psychological and physical state) - it is the hardest and most complicated / complex boss, then if it spares us our life, we will have to monitor our state mental constantly so as not to be changed into a supernaturally unbeatable creature which leads us to the worst end, we take our place at his side in the labyrinth of the abyss,
- Succubus Viccoria (also depending on our mental/psychological and physical state),
- Caleb before recovering his human memory (same for Bernard),
Otherwise, I'm not sure yet, but I think there are more ...