Interesting concept, and I love the Yu-Gi-Oh! theming here. Some nice comedy as well with the evil millennium puzzle stand-in , although having to repeat the same dialogue on repeat whenever you restart was a small niggle. Some of the cards were pretty funny as well (especially comparing your cards to your opponents). The art was serviceable especially for just 48 hours, but having sound effects and background music would've really helped the game.
Overall, nice work!