I wish I didn't just accidentally find this on gamefaqs 10 minutes after I beat Mystic Quest again. I'm super curious about the secret dungeons and bosses.
Viewing post in Memeal Mantasy: Fystic Quest comments
Isn't that always the way stuff like this works? :P
The encouragement I can give you is that Meme Mode changes every box of dialog in the story, so it should feel different. Also, my game undoubtedly runs faster, so it shouldn't take you as long. And, I will say (rather uncharacteristically of me) that I am very proud of those extras.