She should be back on her feet in the next update, which is expected to be in 3 months or so based on past performance. She was hit hard, but she's a survivor, and the entire game is about fixing your girls, it would go against the grain of the story for Maria to become permanently broken.
Whether or not Runey will have the time or inclination to change the scenes in the dungeon to account for her new situation is anybody's guess. In the meantime, if you want to have some dungeon fun with Maria, you will have to load up an old save.