Hey there, sorry you're having issues. What version of After Effects and Windows are you running?
Please doublecheck that you have installed all of the files, in your Script UI Panels folder you should have the gifsquid.jsxbin as well as a Gifsquid folder. Also check in c:\programdata for a file called "squidyavi.bat". If that isn't present after trying to Squirt, it means that GIFsquid wasn't able to write files. If AE is simply not rendering your project after queing an AVI, try rendering it manually or clearing the render queue before squirting.