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Wow that is really weird, even with no input it crashes at 15 minutes.

After some googling I found links with what sounds like a similar thing for other games, and the problems seems to be a process called tabtip32.exe. Can you try killing it if you see it in task manager and follow these steps to disable it:

 1) Open Task Manager

2) Go to Services

3) Identify TabletInputService (Touch Keyboard and Handwriting Panel Service)

4) Stop the service

Links:

https://steamcommunity.com/app/72850/discussions/0/490125737464717517/?ctp=2

http://www.neogaf.com/forum/showthread.php?t=1148961

Also the turn off music and full screen will be saved if you exit the game properly (without crashing). So change those settings and then quit, and it will be saved for next time.