Great work! I liked the top down view of the rooms and there's some great ambiance. Personally not a big fan of combination locks though.
(1.0 in browser) A bug broke the game when I fiddled with the chemistry set in the second act. I put the middle empty vial on the burner and turned it on. I may have left clicked or tried to turn it off again, when the screen went black and I couldn't continue. Hope it's enough to fix it!