Did you install Direct3D 11 and the Visual C++ Redistributable that you could uncheck at the end of the installation? Furthermore, you must be using Windows as the game only runs on that operating system.
Perhaps you have an antivirus program on that stops you from opening the game? Since most games from itch is not a verified publisher, it could be mistaken for a virus. For we tested the game and found no reason as to why it would not launch. If you have any antivirus on, try to temporarily deactivate it while launching the game