The problem with games like these is that the content expand exponentially the more choices you have and longer the game is. You have to be really careful how much different choices really matter. But of course they need to matter. And you have to use clever concept to keep your game in scope.
If you look at games like Detroit: Become human, it starts off slowly and speeds up in the end. The cool thing they did in it was the relationship system. It made every choice seem relevant, while also limiting the possibilities of your actions. It just was too much for a 48h jam