Well, maybe use case is unusual in that I'd like to explore if it can run on OpenBSD, and there's no wine on OpenBSD (and based on prior discussions/efforts never will be), but there's fs-uae. I understand it likely won't be playable based on your description. Would try it anyway just to see - maybe one day computers and/or FS-UAE get faster.
We are essentially limited to open-source games, whatever can run in an emulator, and (lately) FNA games. Tower 57 would be an interesting entry if one day it actually runs okay inside FS-UAE.