A unique game, for sure!
Never seen anything quite like your game, maybe apart from the fight with Undyne in Undertale, but that's a completely different vibe.
I must say, I was really confused at first. It took me a moment to realise the squares in top-left meant what colours were coming next. The fact that the speakers changed colour only as they start shooting, made it really hard to predict or guess where the lasers were coming from. They were absolutely synced up with the music (which was really cool, by the way), but because there was so little time before they started shooting, it felt based more on reflex than rhythm sense. On a complettely different note, what is the slider in the settings? It's not labeled... Again, confusion. My top score was 332, in case you're wondering :)