I do not understand what you mean?
There is a software called butler made by itch https://itch.io/docs/butler/ . It handles uploading to Itch and only uploads the changes made. It also allows you to upload bigger games then via the web interface and game would be hosted by itch not some third party file sharing website. This has the benefit for the user that the itch desktop client can track and (auto) update the game without me having to juggle and clean the download folder.