I have the exact same problem, I tried setting preferences and playing the game on different computer, with and without other mods, and the preferences are ALWAYS wiped when I restart the game like for MissLollypop! It happens with all sims not only the played ones and not only on adults sims, on teens and young adults too :)
I tried just launching the game, setting the preferences, and then immediatly close it and re-launch to see if it would be wiped even if I don't play with the preferences I have set. It wiped it even if I didn't play !